KIF20B Antibody, HRP conjugated (PACO57345)
- SKU:
- PACO57345
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | KIF20B Antibody, HRP conjugated (PACO57345) |
抗体コード: | PACO57345 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Kinesin-like protein KIF20B protein (1607-1731AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Plus-end-directed motor enzyme that is required for completion of cytokinesis. Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression. |
シノニム: | Kinesin-like protein KIF20B (Cancer/testis antigen 90) (CT90) (Kinesin family member 20B) (Kinesin-related motor interacting with PIN1) (M-phase phosphoprotein 1) (MPP1), KIF20B, KRMP1 MPHOSPH1 |
UniProt Protein Function: | Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). |
UniProt Code: | Q96Q89 |
NCBI GenInfo Identifier: | 546231677 |
NCBI Gene ID: | 9585 |
NCBI Accession: | NP_001271188.1 |
UniProt Secondary Accession: | Q96Q89,O43277, Q09471, Q2KQ73, Q32NE1, Q561V3, Q58EX8 Q5T9M8, Q5T9M9, Q5T9N0, Q5T9N1, A8MXM7, |
UniProt Related Accession: | Q96Q89 |
Molecular Weight: | 59,621 Da |
NCBI Full Name: | kinesin-like protein KIF20B isoform 1 |
NCBI Synonym Full Names: | kinesin family member 20B |
NCBI Official Symbol: | KIF20B |
NCBI Official Synonym Symbols: | CT90; MPP1; KRMP1; MPP-1; MPHOSPH1 |
NCBI Protein Information: | kinesin-like protein KIF20B |
UniProt Protein Name: | Kinesin-like protein KIF20B |
UniProt Synonym Protein Names: | Cancer/testis antigen 90; CT90; Kinesin family member 20B |
Protein Family: | Mitochondrial-processing peptidase |
UniProt Gene Name: | KIF20B |