ITSN2 Antibody (PACO48738)
- SKU:
- PACO48738
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ITSN2 Antibody (PACO48738) |
抗体コード: | PACO48738 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Intersectin-2 protein (940-1209AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Hela whole cell lysate, HEK293 whole cell lysate. All lanes: ITSN2 antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 194, 191, 142, 136 kDa. Observed band size: 194, 191, 142 kDa.. | |
Immunofluorescent analysis of HepG2 cells using PACO48738 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes. |
シノニム: | Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein), ITSN2, KIAA1256 SH3D1B SWAP |
UniProt Protein Function: | Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes (PubMed:23999003). |
NCBI Summary: | This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. [provided by RefSeq, Jan 2017] |
UniProt Code: | Q9NZM3 |
NCBI GenInfo Identifier: | 194294521 |
NCBI Gene ID: | 50618 |
NCBI Accession: | NP_006268.2 |
UniProt Secondary Accession: | Q9NZM3,O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2 Q9ULG4, |
UniProt Related Accession: | Q9NZM3 |
Molecular Weight: | 193 kDa |
NCBI Full Name: | intersectin-2 isoform 1 |
NCBI Synonym Full Names: | intersectin 2 |
NCBI Official Symbol: | ITSN2 |
NCBI Official Synonym Symbols: | SWA; SWAP; SH3D1B; SH3P18; PRO2015 |
NCBI Protein Information: | intersectin-2 |
UniProt Protein Name: | Intersectin-2 |
UniProt Synonym Protein Names: | SH3 domain-containing protein 1B; SH3P18; SH3P18-like WASP-associated protein |
Protein Family: | Intersectin |
UniProt Gene Name: | ITSN2 |
Antibodies |
Anti-ITSN2 Antibody (CAB16525) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |