ITIH4 Antibody, HRP conjugated (PACO27698)
- SKU:
- PACO27698
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | ITIH4 Antibody, HRP conjugated (PACO27698) |
抗体コード: | PACO27698 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H4 protein (689-930AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. |
シノニム: | Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4], ITIH4, IHRP ITIHL1 PK120 |
UniProt Protein Function: | ITIH4: May be involved in acute phase reactions. Belongs to the ITIH family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 3p21.1 Cellular Component: extracellular region Molecular Function:endopeptidase inhibitor activity; protein binding Biological Process: acute-phase response; platelet degranulation; response to cytokine stimulus Disease: Hypercholesterolemia, Familial |
NCBI Summary: | The protein encoded by this gene is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
UniProt Code: | Q14624 |
NCBI GenInfo Identifier: | 229463048 |
NCBI Gene ID: | 3700 |
NCBI Accession: | Q14624.4 |
UniProt Secondary Accession: | Q14624,Q15135, Q9P190, Q9UQ54, B7Z545, E9PGN5, |
UniProt Related Accession: | Q14624 |
Molecular Weight: | 93,852 Da |
NCBI Full Name: | Inter-alpha-trypsin inhibitor heavy chain H4 |
NCBI Synonym Full Names: | inter-alpha-trypsin inhibitor heavy chain family member 4 |
NCBI Official Symbol: | ITIH4 |
NCBI Official Synonym Symbols: | H4P; IHRP; GP120; PK120; ITIHL1; PK-120; ITI-HC4 |
NCBI Protein Information: | inter-alpha-trypsin inhibitor heavy chain H4 |
UniProt Protein Name: | Inter-alpha-trypsin inhibitor heavy chain H4 |
UniProt Synonym Protein Names: | Inter-alpha-trypsin inhibitor family heavy chain-related protein; IHRP |
Protein Family: | Inter alpha-trypsin inhibitor |
UniProt Gene Name: | ITIH4 |
UniProt Entry Name: | ITIH4_HUMAN |