HOOK1 Antibody, HRP conjugated (PACO42371)
- SKU:
- PACO42371
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | HOOK1 Antibody, HRP conjugated (PACO42371) |
抗体コード: | PACO42371 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Protein Hook homolog 1 protein (301-600AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton. Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). |
シノニム: | Protein Hook homolog 1 (h-hook1) (hHK1), HOOK1 |
UniProt Protein Function: | HOOK1: Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton. Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Belongs to the hook family. |
UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 1p32.1 Molecular Function:identical protein binding; protein binding Biological Process: early endosome to late endosome transport; endosome organization and biogenesis; endosome to lysosome transport; lysosome organization and biogenesis |
NCBI Summary: | This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UJC3 |
NCBI GenInfo Identifier: | 41688595 |
NCBI Gene ID: | 51361 |
NCBI Accession: | Q9UJC3.2 |
UniProt Secondary Accession: | Q9UJC3,O60561, Q5TG44, A8K8E9, A8MU44, B4DX15, |
UniProt Related Accession: | Q9UJC3 |
Molecular Weight: | 80,021 Da |
NCBI Full Name: | Protein Hook homolog 1 |
NCBI Synonym Full Names: | hook microtubule tethering protein 1 |
NCBI Official Symbol: | HOOK1 |
NCBI Official Synonym Symbols: | HK1 |
NCBI Protein Information: | protein Hook homolog 1 |
UniProt Protein Name: | Protein Hook homolog 1 |
Protein Family: | Protein Hook |
UniProt Gene Name: | HOOK1 |
UniProt Entry Name: | HOOK1_HUMAN |