HNRNPF Antibody, Biotin conjugated (PACO45909)
- SKU:
- PACO45909
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | HNRNPF Antibody, Biotin conjugated (PACO45909) |
抗体コード: | PACO45909 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Heterogeneous nuclear ribonucleoprotein F protein (186-336AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state. |
シノニム: | Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed], HNRNPF, HNRPF |
UniProt Protein Function: | hnRNP F: Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state. |
UniProt Protein Details: | Protein type:Spliceosome; RNA splicing; RNA-binding Chromosomal Location of Human Ortholog: 10q11.21 Cellular Component: nucleoplasm; membrane; nucleus Molecular Function:protein binding; single-stranded RNA binding; RNA binding; nucleotide binding Biological Process: RNA processing; nuclear mRNA splicing, via spliceosome; regulation of RNA splicing; RNA splicing; gene expression |
NCBI Summary: | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | P52597 |
NCBI GenInfo Identifier: | 1710628 |
NCBI Gene ID: | 3185 |
NCBI Accession: | P52597.3 |
UniProt Secondary Accession: | P52597,Q5T0N2, Q96AU2, B3KM84, |
UniProt Related Accession: | P52597 |
Molecular Weight: | 415 |
NCBI Full Name: | Heterogeneous nuclear ribonucleoprotein F |
NCBI Synonym Full Names: | heterogeneous nuclear ribonucleoprotein F |
NCBI Official Symbol: | HNRNPF |
NCBI Official Synonym Symbols: | HNRPF; mcs94-1; OK/SW-cl.23 |
NCBI Protein Information: | heterogeneous nuclear ribonucleoprotein F; HnRNP F protein; nucleolin-like protein mcs94-1 |
UniProt Protein Name: | Heterogeneous nuclear ribonucleoprotein F |
UniProt Synonym Protein Names: | Nucleolin-like protein mcs94-1Heterogeneous nuclear ribonucleoprotein F, N-terminally processed |
Protein Family: | Heterogeneous nuclear ribonucleoprotein |
UniProt Gene Name: | HNRNPF |
UniProt Entry Name: | HNRPF_HUMAN |