HMMR Antibody (PACO55074)
- SKU:
- PACO55074
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HMMR Antibody (PACO55074) |
抗体コード: | PACO55074 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Hyaluronan mediated motility receptor protein (478-653AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human breast cancer using PACO55074 at dilution of 1:100. | |
Immunofluorescent analysis of HepG2 cells using PACO55074 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. |
シノニム: | Hyaluronan mediated motility receptor (Intracellular hyaluronic acid, binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168), HMMR, IHABP RHAMM |
UniProt Protein Function: | HMMR: Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Receptor, misc. Chromosomal Location of Human Ortholog: 5q34 Cellular Component: cell surface; membrane; cytoplasm; plasma membrane Molecular Function:hyaluronic acid binding Biological Process: glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis; hyaluronan metabolic process; hyaluronan catabolic process Disease: Breast Cancer |
NCBI Summary: | The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008] |
UniProt Code: | O75330 |
NCBI GenInfo Identifier: | 145559482 |
NCBI Gene ID: | 3161 |
NCBI Accession: | O75330.2 |
UniProt Secondary Accession: | O75330,Q32N02, Q92767, A8K3G2, B4E114, D3DQK9, D3DQL0 E9PCS0, |
UniProt Related Accession: | O75330 |
Molecular Weight: | |
NCBI Full Name: | Hyaluronan mediated motility receptor |
NCBI Synonym Full Names: | hyaluronan-mediated motility receptor (RHAMM) |
NCBI Official Symbol: | HMMR |
NCBI Official Synonym Symbols: | CD168; IHABP; RHAMM |
NCBI Protein Information: | hyaluronan mediated motility receptor; receptor for hyaluronan-mediated motility; intracellular hyaluronic acid-binding protein |
UniProt Protein Name: | Hyaluronan mediated motility receptor |
UniProt Synonym Protein Names: | Intracellular hyaluronic acid-binding protein; Receptor for hyaluronan-mediated motility; CD_antigen: CD168 |
Protein Family: | Hyaluronan mediated motility receptor |
UniProt Gene Name: | HMMR |
UniProt Entry Name: | HMMR_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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