HK3 Antibody (PACO15705)
- SKU:
- PACO15705
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HK3 Antibody (PACO15705) |
抗体コード: | PACO15705 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human HK3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO15705(HK3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO15705(HK3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. |
シノニム: | hexokinase 3 (white cell) |
UniProt Protein Function: | HK3: a glycolytic enzyme that catalyzes the reaction ATP + D-hexose = ADP + D-hexose 6-phosphate. The first and rate-limiting step in glycosis, a pathway that produces energy in the form of ATP from glucose. An allosteric enzyme inhibited by its product glucose-6-phosphate (Glc-6-P). Acts as a ""glucose sensor"" by trapping glucose inside the cell by catalyzing its phosphorylation to produce Glc-6-P. In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). |
UniProt Protein Details: | Protein type:Transferase; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Enzyme, cellular metabolism; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - fructose and mannose; EC 2.7.1.1; Kinase, other; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - galactose Chromosomal Location of Human Ortholog: 5q35.2 Cellular Component: cytosol Molecular Function:fructokinase activity; glucokinase activity; hexokinase activity; mannokinase activity Biological Process: cell glucose homeostasis; glucose transport; glycolysis |
NCBI Summary: | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009] |
UniProt Code: | P52790 |
NCBI GenInfo Identifier: | 206729871 |
NCBI Gene ID: | 3101 |
NCBI Accession: | P52790.2 |
UniProt Secondary Accession: | P52790,Q8N1E7, |
UniProt Related Accession: | P52790 |
Molecular Weight: | 99,025 Da |
NCBI Full Name: | Hexokinase-3 |
NCBI Synonym Full Names: | hexokinase 3 |
NCBI Official Symbol: | HK3 |
NCBI Official Synonym Symbols: | HXK3; HKIII |
NCBI Protein Information: | hexokinase-3 |
UniProt Protein Name: | Hexokinase-3 |
UniProt Synonym Protein Names: | Hexokinase type III; HK III |
Protein Family: | Probable histidine kinase |
UniProt Gene Name: | HK3 |
UniProt Entry Name: | HXK3_HUMAN |
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