HDAC10 Antibody (PACO47454)
- SKU:
- PACO47454
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | HDAC10 Antibody (PACO47454) |
抗体コード: | PACO47454 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Histone deacetylase 10 protein (207-412AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Mouse liver tissue. All lanes: HDAC10 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 72, 70, 71, 44 kDa. Observed band size: 72, 34 kDa.. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO47454 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO47454 at dilution of 1:100. |
バックグラウンド: | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. |
シノニム: | Histone deacetylase 10 (HD10) (EC 3.5.1.98), HDAC10 |
UniProt Protein Function: | HDAC10: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Belongs to the histone deacetylase family. HD type 2 subfamily. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor; Deacetylase; EC 3.5.1.98 Chromosomal Location of Human Ortholog: 22q13.31 Cellular Component: nucleoplasm; histone deacetylase complex; cytoplasm; nucleus Molecular Function:NAD-dependent histone deacetylase activity (H3-K9 specific); protein binding; enzyme binding; NAD-dependent histone deacetylase activity (H3-K14 specific); histone deacetylase binding; protein deacetylase activity; NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity Biological Process: establishment and/or maintenance of chromatin architecture; Notch signaling pathway; transcription, DNA-dependent; regulation of transcription, DNA-dependent; protein amino acid deacetylation; histone deacetylation; chromatin modification; negative regulation of transcription from RNA polymerase II promoter; oligodendrocyte development; negative regulation of transcription, DNA-dependent |
NCBI Summary: | The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
UniProt Code: | Q969S8 |
NCBI GenInfo Identifier: | 27734403 |
NCBI Gene ID: | 83933 |
NCBI Accession: | Q969S8.1 |
UniProt Secondary Accession: | Q969S8,Q08AP4, Q6STF9, Q96P77, Q96P78, Q9H028, Q9UGX1 Q9UGX2, |
UniProt Related Accession: | Q969S8 |
Molecular Weight: | 669 |
NCBI Full Name: | Histone deacetylase 10 |
NCBI Synonym Full Names: | histone deacetylase 10 |
NCBI Official Symbol: | HDAC10 |
NCBI Official Synonym Symbols: | HD10 |
NCBI Protein Information: | histone deacetylase 10 |
UniProt Protein Name: | Histone deacetylase 10 |
Protein Family: | Histone deacetylase |
UniProt Gene Name: | HDAC10 |
UniProt Entry Name: | HDA10_HUMAN |
Antibodies | ELISA Kits |
Anti-HDAC10 Antibody (CAB6184) | HDAC10 Colorimetric Cell-Based ELISA Kit |
HDAC10 Antibody (PACO00909) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |