GTF2A1 Antibody (PACO04002)
- SKU:
- PACO04002
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GTF2A1 Antibody |
抗体コード: | PACO04002 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from the C-terminal region of human TFIIA-alpha. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | GTF2A1; TF2A1; Transcription initiation factor IIA subunit 1; General transcription factor IIA subunit 1; TFIIAL; Transcription initiation factor TFIIA 42 kDa subunit; TFIIA-42 |
UniProt Protein Function: | GTF2A1: a general transcription factor that plays an important role in transcriptional activation. A component of the transcription machinery of RNA polymerase II. Phosphorylated by Taf(II) 250 on serines that regulate TBP binding. Interacts with TBP (the TATA-binding protein). Two isoforms, 42 kDa and 37 kDa, are produced by alternative initiation. |
UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 14q31.1 Cellular Component: cytoplasm; nucleoplasm; transcription factor TFIIA complex Molecular Function:DNA binding; protein binding; protein heterodimerization activity; TATA-binding protein binding; transcription coactivator activity; transcription factor binding Biological Process: RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter |
NCBI Summary: | Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010] |
UniProt Code: | P52655 |
NCBI GenInfo Identifier: | 1711663 |
NCBI Gene ID: | 2957 |
NCBI Accession: | P52655.1 |
UniProt Secondary Accession: | P52655,Q3KNQ9, |
UniProt Related Accession: | P52655 |
Molecular Weight: | 37,152 Da |
NCBI Full Name: | Transcription initiation factor IIA subunit 1 |
NCBI Synonym Full Names: | general transcription factor IIA subunit 1 |
NCBI Official Symbol: | GTF2A1 |
NCBI Official Synonym Symbols: | TF2A1; TFIIA; TFIIAL; TFIIA-42 |
NCBI Protein Information: | transcription initiation factor IIA subunit 1 |
UniProt Protein Name: | Transcription initiation factor IIA subunit 1 |
UniProt Synonym Protein Names: | General transcription factor IIA subunit 1; TFIIAL; Transcription initiation factor TFIIA 42 kDa subunit; TFIIA-42 |
Protein Family: | Transcription initiation factor |
UniProt Gene Name: | GTF2A1 |
UniProt Entry Name: | TF2AA_HUMAN |