GPM6A Antibody (PACO15730)
- SKU:
- PACO15730
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GPM6A Antibody (PACO15730) |
抗体コード: | PACO15730 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human GPM6A |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15730(GPM6A Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane: Human fetal brain tissue, Primary antibody: PACO15730(GPM6A Antibody) at dilution 1/1050, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second. | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15730(GPM6A Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. |
シノニム: | glycoprotein M6A |
UniProt Protein Function: | GPM6A: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. Belongs to the myelin proteolipid protein family. |
UniProt Protein Details: | Protein type:Cell surface; Channel, calcium; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 4q34.2 Cellular Component: cell soma; filopodium; neuron projection; plasma membrane Molecular Function:protein binding Biological Process: neurite morphogenesis; neuron migration; positive regulation of filopodium formation; stem cell differentiation; synaptogenesis |
UniProt Code: | P51674 |
NCBI GenInfo Identifier: | 2506889 |
NCBI Gene ID: | 2823 |
NCBI Accession: | P51674.2 |
UniProt Secondary Accession: | P51674,Q92602, B7Z642, E9PHI5, |
UniProt Related Accession: | P51674 |
Molecular Weight: | 31kDa |
NCBI Full Name: | Neuronal membrane glycoprotein M6-a |
NCBI Synonym Full Names: | glycoprotein M6A |
NCBI Official Symbol: | GPM6A |
NCBI Official Synonym Symbols: | M6A; GPM6 |
NCBI Protein Information: | neuronal membrane glycoprotein M6-a |
UniProt Protein Name: | Neuronal membrane glycoprotein M6-a |
Protein Family: | Neuronal membrane glycoprotein |
UniProt Gene Name: | GPM6A |