GMPPB Antibody (PACO42694)
- SKU:
- PACO42694
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GMPPB Antibody (PACO42694) |
抗体コード: | PACO42694 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Mannose-1-phosphate guanyltransferase β protein (61-360AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO42694 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO42694 at dilution of 1:100. |
バックグラウンド: | cytoplasm, extracellular exosome, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, GDP-mannose biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine |
シノニム: | Mannose-1-phosphate guanyltransferase β (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta), GMPPB |
UniProt Protein Function: | GMPPB: This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2009] |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 2.7.7.13; Carbohydrate Metabolism - fructose and mannose; Transferase Chromosomal Location of Human Ortholog: 3p21.31 Cellular Component: cytoplasm Molecular Function:protein binding Disease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 14; Muscular Dystrophy-dystroglycanopathy (congenital With Mental Retardation), Type B, 14; Muscular Dystrophy-dystroglycanopathy (limb-girdle), Type C, 14 |
NCBI Summary: | This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2009] |
UniProt Code: | Q9Y5P6 |
NCBI GenInfo Identifier: | 160013885 |
NCBI Gene ID: | 29925 |
NCBI Accession: | Q9Y5P6.2 |
UniProt Secondary Accession: | Q9Y5P6,Q9H7U3, A8K6N5, |
UniProt Related Accession: | Q9Y5P6 |
Molecular Weight: | 42,622 Da |
NCBI Full Name: | Mannose-1-phosphate guanyltransferase beta |
NCBI Synonym Full Names: | GDP-mannose pyrophosphorylase B |
NCBI Official Symbol: | GMPPB |
NCBI Official Synonym Symbols: | MDDGA14; MDDGB14; MDDGC14 |
NCBI Protein Information: | mannose-1-phosphate guanyltransferase beta |
UniProt Protein Name: | Mannose-1-phosphate guanyltransferase beta |
UniProt Synonym Protein Names: | GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta |
Protein Family: | Mannose-1-phosphate guanyltransferase |
UniProt Gene Name: | GMPPB |
UniProt Entry Name: | GMPPB_HUMAN |