GABRB3 Antibody (PACO49614)
- SKU:
- PACO49614
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GABRB3 Antibody (PACO49614) |
抗体コード: | PACO49614 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Gamma-aminobutyric acid, receptor subunit beta-3 protein (328-450AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: HepG2 whole cell lysate. All lanes: GABRB3 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 55, 47, 46 kDa. Observed band size: 55 kDa.. | |
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO49614 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO49614 at dilution of 1:100. |
バックグラウンド: | Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel. |
シノニム: | Gamma-aminobutyric acid, receptor subunit beta-3 (GABA(A) receptor subunit beta-3), GABRB3 |
UniProt Protein Function: | Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel. |
NCBI Summary: | This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013] |
UniProt Code: | P28472 |
NCBI GenInfo Identifier: | 4503867 |
NCBI Gene ID: | 2562 |
NCBI Accession: | NP_000805.1 |
UniProt Secondary Accession: | P28472,Q14352, Q96FM5, B7Z2W1, B7Z825, F5H3D2, H7BYV8 |
UniProt Related Accession: | P28472 |
Molecular Weight: | 54,379 Da |
NCBI Full Name: | gamma-aminobutyric acid receptor subunit beta-3 isoform 1 |
NCBI Synonym Full Names: | gamma-aminobutyric acid type A receptor beta3 subunit |
NCBI Official Symbol: | GABRB3 |
NCBI Official Synonym Symbols: | ECA5; EIEE43 |
NCBI Protein Information: | gamma-aminobutyric acid receptor subunit beta-3 |
UniProt Protein Name: | Gamma-aminobutyric acid receptor subunit beta-3 |
UniProt Synonym Protein Names: | GABA(A) receptor subunit beta-3 |
Protein Family: | Gamma-aminobutyric acid receptor |
UniProt Gene Name: | GABRB3 |
Antibodies |
Anti-GABRB3 Antibody (CAB10015) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |