FXR1 Antibody (PACO19681)
- SKU:
- PACO19681
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | FXR1 Antibody (PACO19681) |
抗体コード: | PACO19681 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human FXR1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19681(FXR1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: 231 cells, Primary antibody: PACO19681(FXR1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19681(FXR1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene |
シノニム: | fragile X mental retardation, autosomal homolog 1 |
UniProt Protein Function: | FXR1: RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs. Interacts with FMR1 and FXR2. Interacts with TDRD3, and with CYFIP2 but not with CYFIP1. Expressed in all tissues examined including heart, brain, kidney and testis. Belongs to the FMR1 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Translation; RNA-binding Chromosomal Location of Human Ortholog: 3q28 Cellular Component: polysome; costamere; membrane; cytoplasm; nucleolus Molecular Function:mRNA binding; mRNA 3'-UTR binding; RNA binding Biological Process: muscle development; apoptosis; negative regulation of translation; cell differentiation |
NCBI Summary: | The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P51114 |
NCBI GenInfo Identifier: | 189047132 |
NCBI Gene ID: | 8087 |
NCBI Accession: | P51114.3 |
UniProt Secondary Accession: | P51114,Q7Z450, Q8N6R8, A8K9B8, |
UniProt Related Accession: | P51114 |
Molecular Weight: | 621 |
NCBI Full Name: | Fragile X mental retardation syndrome-related protein 1 |
NCBI Synonym Full Names: | fragile X mental retardation, autosomal homolog 1 |
NCBI Official Symbol: | FXR1 |
NCBI Official Synonym Symbols: | FXR1P |
NCBI Protein Information: | fragile X mental retardation syndrome-related protein 1; hFXR1p |
UniProt Protein Name: | Fragile X mental retardation syndrome-related protein 1 |
Protein Family: | Fragile X mental retardation syndrome-related protein |
UniProt Gene Name: | FXR1 |
UniProt Entry Name: | FXR1_HUMAN |
Antibodies |
Anti-FXR1 Antibody (CAB16447) |
Anti-FXR1 Antibody (CAB5942) |
Anti-FXR1 Antibody (CAB8697) |
FXR1 Antibody (PACO09365) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |