FTSJ1 Antibody (PACO26841)
- SKU:
- PACO26841
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | FTSJ1 Antibody (PACO26841) |
抗体コード: | PACO26841 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase protein (1-329AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: FTSJ1 antibody at 2µg/ml Lane 1: HepG2 whole cell lysate Lane 2: Mouse brain tissue Lane 3: EC109 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 37, 36 kDa Observed band size: 37 kDa . | |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO26841 at dilution of 1:50. |
バックグラウンド: | Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs |
シノニム: | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (Protein ftsJ homolog 1), FTSJ1 |
UniProt Protein Function: | FTSJ1: Defects in FTSJ1 are the cause of mental retardation X- linked type 44 (MRX44). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Belongs to the methyltransferase superfamily. RlmE family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.1.1.205; Methyltransferase Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: cytoplasm Molecular Function:tRNA methyltransferase activity Biological Process: tRNA methylation Disease: Mental Retardation, X-linked 9 |
NCBI Summary: | This gene encodes a member of the methyltransferase superfamily. The encoded protein localizes to the nucleolus, binds to S-adenosylmethionine, and may be involved in the processing and modification of ribosomal RNA. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q9UET6 |
NCBI GenInfo Identifier: | 12643879 |
NCBI Gene ID: | 24140 |
NCBI Accession: | Q9UET6.2 |
UniProt Secondary Accession: | Q9UET6,O75670, B2RCJ0, |
UniProt Related Accession: | Q9UET6 |
Molecular Weight: | 35,867 Da |
NCBI Full Name: | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase |
NCBI Synonym Full Names: | FtsJ RNA methyltransferase homolog 1 (E. coli) |
NCBI Official Symbol: | FTSJ1 |
NCBI Official Synonym Symbols: | JM23; MRX9; SPB1; CDLIV; MRX44; TRMT7 |
NCBI Protein Information: | putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase |
UniProt Protein Name: | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase |
UniProt Synonym Protein Names: | 2'-O-ribose RNA methyltransferase TRM7 homolog |
UniProt Gene Name: | FTSJ1 |
UniProt Entry Name: | TRM7_HUMAN |
Antibodies |
Anti-FTSJ1 Antibody (CAB7967) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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