FSCN1 Antibody (PACO01925)
- SKU:
- PACO01925
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | FSCN1 Antibody |
抗体コード: | PACO01925 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from the Internal region of human Fascin 1. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | FSCN1; FAN1; HSN; SNL; Fascin; 55 kDa actin-bundling protein; Singed-like protein; p55 |
UniProt Protein Function: | Fascin: Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Associates with beta-catenin. Ubiquitous. Belongs to the fascin family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal; Actin-binding Chromosomal Location of Human Ortholog: 7p22 Cellular Component: cytoplasm; stress fiber; cell junction; cytosol; actin cytoskeleton; filopodium Molecular Function:protein binding, bridging; actin filament binding; protein binding; drug binding; actin binding Biological Process: cell proliferation; actin filament bundle formation; cell migration; cell motility involved in cell locomotion; actin cytoskeleton organization and biogenesis |
NCBI Summary: | This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011] |
UniProt Code: | Q16658 |
NCBI GenInfo Identifier: | 2498357 |
NCBI Gene ID: | 6624 |
NCBI Accession: | Q16658.3 |
UniProt Related Accession: | Q16658 |
Molecular Weight: | 54kDa |
NCBI Full Name: | Fascin |
NCBI Synonym Full Names: | fascin actin-bundling protein 1 |
NCBI Official Symbol: | FSCN1 |
NCBI Official Synonym Symbols: | HSN; SNL; p55; FAN1 |
NCBI Protein Information: | fascin |
UniProt Protein Name: | Fascin |
UniProt Synonym Protein Names: | 55 kDa actin-bundling protein; Singed-like protein; p55 |
Protein Family: | Fascin |
UniProt Gene Name: | FSCN1 |
UniProt Entry Name: | FSCN1_HUMAN |