UniProt Protein Function: | FRK: a tyrosine kinase of the Src family. Expressed in cell lines derived from tissues of lymphoid, brain, breast, colon and bladder origin. A nuclear protein that may function during G1 and S phase of the cell cycle to suppress growth. |
UniProt Protein Details: | Protein type:EC 2.7.10.2; Tumor suppressor; Protein kinase, tyrosine (non-receptor); Kinase, protein; Protein kinase, TK; TK group; Src family Chromosomal Location of Human Ortholog: 6q21-q22.3 Cellular Component: cytoplasm; extrinsic to internal side of plasma membrane; intracellular; intracellular membrane-bound organelle; nucleus Molecular Function:protein binding; receptor binding Biological Process: cell differentiation; innate immune response; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway |
NCBI Summary: | The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008] |
UniProt Code: | P42685 |
NCBI GenInfo Identifier: | 1169745 |
NCBI Gene ID: | 2444 |
NCBI Accession: | P42685.1 |
UniProt Secondary Accession: | P42685,Q13128, Q9NTR5, B4DY49, |
UniProt Related Accession: | P42685 |
Molecular Weight: | 41,980 Da |
NCBI Full Name: | Tyrosine-protein kinase FRK |
NCBI Synonym Full Names: | fyn related Src family tyrosine kinase |
NCBI Official Symbol: | FRK |
NCBI Official Synonym Symbols: | GTK; RAK; PTK5 |
NCBI Protein Information: | tyrosine-protein kinase FRK |
UniProt Protein Name: | Tyrosine-protein kinase FRK |
UniProt Synonym Protein Names: | FYN-related kinase; Nuclear tyrosine protein kinase RAK; Protein-tyrosine kinase 5 |
Protein Family: | Tyrosine-protein kinase |
UniProt Gene Name: | FRK |
UniProt Entry Name: | FRK_HUMAN |