FLT3LG Antibody, HRP conjugated (PACO26794)
- SKU:
- PACO26794
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | FLT3LG Antibody, HRP conjugated (PACO26794) |
抗体コード: | PACO26794 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Fms-related tyrosine kinase 3 ligand protein (27-184AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. |
シノニム: | Fms-related tyrosine kinase 3 ligand (Flt3 ligand) (Flt3L) (SL cytokine), FLT3LG |
UniProt Protein Function: | FLT3LG: Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cytokine; Ligand, receptor tyrosine kinase; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: extracellular space; membrane; integral to membrane Molecular Function:protein homodimerization activity; cytokine activity; receptor tyrosine kinase binding; receptor binding Biological Process: regulation of myeloid dendritic cell activation; positive regulation of natural killer cell differentiation; lymphocyte differentiation; embryonic hemopoiesis; positive regulation of cell proliferation; positive regulation of protein amino acid phosphorylation; signal transduction; positive regulation of myoblast differentiation |
NCBI Summary: | Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011] |
UniProt Code: | P49771 |
NCBI GenInfo Identifier: | 1706818 |
NCBI Gene ID: | 2323 |
NCBI Accession: | P49771.1 |
UniProt Secondary Accession: | P49771,Q05C96, A0AVC2, B9EGH2, |
UniProt Related Accession: | P49771 |
Molecular Weight: | approximately 150 kDa |
NCBI Full Name: | Fms-related tyrosine kinase 3 ligand |
NCBI Synonym Full Names: | fms-related tyrosine kinase 3 ligand |
NCBI Official Symbol: | FLT3LG |
NCBI Official Synonym Symbols: | FL; FLT3L |
NCBI Protein Information: | fms-related tyrosine kinase 3 ligand; flt3 ligand |
UniProt Protein Name: | Fms-related tyrosine kinase 3 ligand |
UniProt Synonym Protein Names: | SL cytokine |
Protein Family: | Receptor-type tyrosine-protein kinase |
UniProt Gene Name: | FLT3LG |
UniProt Entry Name: | FLT3L_HUMAN |