FEM1B Antibody (PACO19652)
- SKU:
- PACO19652
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | FEM1B Antibody (PACO19652) |
抗体コード: | PACO19652 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human FEM1B |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: PC3 cells, Primary antibody: PACO19652(FEM1B Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19652(FEM1B Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1 |
シノニム: | fem-1 homolog b (C. elegans) |
UniProt Protein Function: | FEM1B: Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1. Belongs to the fem-1 family. |
UniProt Protein Details: | Protein type:Apoptosis; Cell development/differentiation; Ligase; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 15q23 Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus Molecular Function:death receptor binding; protein binding; ubiquitin-protein ligase activity Biological Process: regulation of ubiquitin-protein ligase activity |
NCBI Summary: | This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q9UK73 |
NCBI GenInfo Identifier: | 74753369 |
NCBI Gene ID: | 10116 |
NCBI Accession: | Q9UK73.1 |
UniProt Secondary Accession: | Q9UK73,O43146, |
UniProt Related Accession: | Q9UK73 |
Molecular Weight: | 70kDa |
NCBI Full Name: | Protein fem-1 homolog B |
NCBI Synonym Full Names: | fem-1 homolog B |
NCBI Official Symbol: | FEM1B |
NCBI Official Synonym Symbols: | F1AA; F1A-ALPHA; FEM1-beta |
NCBI Protein Information: | protein fem-1 homolog B |
UniProt Protein Name: | Protein fem-1 homolog B |
UniProt Synonym Protein Names: | FEM1-beta; Fem-1-like death receptor-binding protein alpha; Fem-1-like in apoptotic pathway protein alpha; F1A-alpha |
UniProt Gene Name: | FEM1B |