FCGR2B Antibody, HRP conjugated (PACO46391)
- SKU:
- PACO46391
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | FCGR2B Antibody, HRP conjugated (PACO46391) |
抗体コード: | PACO46391 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Low affinity immunoglobulin γ Fc region receptor II-b protein (12-289AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. |
シノニム: | Low affinity immunoglobulin γ Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-γ RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32), FCGR2B, CD32 FCG2 IGFR2 |
NCBI Summary: | The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
UniProt Code: | P31994 |
NCBI GenInfo Identifier: | |
NCBI Gene ID: | 2213 |
NCBI Accession: | |
UniProt Related Accession: | P31994 |
Molecular Weight: | |
NCBI Full Name: | |
NCBI Synonym Full Names: | Fc fragment of IgG receptor IIb |
NCBI Official Symbol: | FCGR2B |
NCBI Official Synonym Symbols: | CD32; FCG2; CD32B; FCGR2; IGFR2; FCGR2C; FcRII-c |
NCBI Protein Information: | low affinity immunoglobulin gamma Fc region receptor II-b |
UniProt Protein Name: | |
Protein Family: | CD320 antigen |
UniProt Gene Name: |