FAM107A Antibody, HRP conjugated (PACO26642)
- SKU:
- PACO26642
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | FAM107A Antibody, HRP conjugated (PACO26642) |
抗体コード: | PACO26642 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Actin-associated protein FAM107A protein (1-144AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity). Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal adhesion (FA) assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner (PubMed:20543869). Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner (PubMed:10564580, PubMed:28604741). May play a role in tumor development (PubMed:10564580). |
シノニム: | Actin-associated protein FAM107A (Down-regulated in renal cell carcinoma 1) (Protein TU3A), FAM107A, DRR1 TU3A |
UniProt Code: | O95990 |
NCBI GenInfo Identifier: | 115583665 |
NCBI Gene ID: | 11170 |
NCBI Accession: | NP_001070246.1 |
UniProt Secondary Accession: | O95990,Q96NH4, B3KNQ4, B7ZAY5, J3KR61, |
UniProt Related Accession: | O95990 |
Molecular Weight: | 17,455 Da |
NCBI Full Name: | protein FAM107A isoform a |
NCBI Synonym Full Names: | family with sequence similarity 107, member A |
NCBI Official Symbol: | FAM107A |
NCBI Official Synonym Symbols: | DRR1; TU3A |
NCBI Protein Information: | protein FAM107A; down-regulated in renal cell carcinoma 1 |
UniProt Protein Name: | Protein FAM107A |
UniProt Synonym Protein Names: | Down-regulated in renal cell carcinoma 1; Protein TU3A |
UniProt Gene Name: | FAM107A |
UniProt Entry Name: | F107A_HUMAN |