FAF1 Antibody, FITC conjugated (PACO48804)
- SKU:
- PACO48804
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Description
抗体名: | FAF1 Antibody, FITC conjugated (PACO48804) |
抗体コード: | PACO48804 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human FAS-associated factor 1 protein (490-629AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Potentiates but cannot initiate FAS-induced apoptosis. |
シノニム: | FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A), FAF1, UBXD12 UBXN3A |
UniProt Protein Function: | FAF1: a pro-apoptotic protein that binds to FAS antigen. Potentiates but cannot initiate FAS-induced apoptosis. Its pro-apoptotic activity requires a ubiquitin-like domain but not the FAS-binding domain. Phosphorylation by protein kinase CK2 influences transport into nucleus. Two transcript variants encoding different protein isoforms have been described. |
UniProt Protein Details: | Protein type:Apoptosis; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 1p33 Cellular Component: perinuclear region of cytoplasm; CD95 death-inducing signaling complex; nuclear envelope; nucleus; cytosol Molecular Function:NF-kappaB binding; protein domain specific binding; protein binding; ubiquitin binding; ubiquitin protein ligase binding; heat shock protein binding; protein kinase regulator activity; protein kinase binding Biological Process: regulation of cell adhesion; cell death; proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein complex assembly; cytoplasmic sequestering of NF-kappaB; positive regulation of apoptosis; apoptosis; regulation of protein catabolic process; regulation of protein kinase activity |
NCBI Summary: | Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UNN5 |
NCBI GenInfo Identifier: | 20454906 |
NCBI Gene ID: | 11124 |
NCBI Accession: | Q9UNN5.2 |
UniProt Secondary Accession: | Q9UNN5,Q549F0, Q9UF34, Q9UNT3, Q9Y2Z3, |
UniProt Related Accession: | Q9UNN5 |
Molecular Weight: | 650 |
NCBI Full Name: | FAS-associated factor 1 |
NCBI Synonym Full Names: | Fas (TNFRSF6) associated factor 1 |
NCBI Official Symbol: | FAF1 |
NCBI Official Synonym Symbols: | hFAF1; CGI-03; HFAF1s; UBXD12; UBXN3A |
NCBI Protein Information: | FAS-associated factor 1; UBX domain protein 3A; TNFRSF6-associated factor 1; UBX domain-containing protein 12; UBX domain-containing protein 3A |
UniProt Protein Name: | FAS-associated factor 1 |
UniProt Synonym Protein Names: | UBX domain-containing protein 12; UBX domain-containing protein 3A |
Protein Family: | FAS-associated factor |
UniProt Gene Name: | FAF1 |
UniProt Entry Name: | FAF1_HUMAN |