ETV7 Antibody (PACO16282)
- SKU:
- PACO16282
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ETV7 Antibody (PACO16282) |
抗体コード: | PACO16282 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
反応性: | Human, Mouse |
免疫原: | Fusion protein of human ETV7 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16282(ETV7 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 293T cells, LoVo cells, mouse skin tissue, A172 cells, Primary antibody: PACO16282(ETV7 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO16282(ETV7 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene |
シノニム: | ets variant 7 |
UniProt Protein Function: | ETV7: Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity. Belongs to the ETS family. 8 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 6p21 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; organ morphogenesis; negative regulation of transcription from RNA polymerase II promoter; cell differentiation |
NCBI Summary: | The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).[provided by RefSeq, May 2011] |
UniProt Code: | Q9Y603 |
NCBI GenInfo Identifier: | 13124589 |
NCBI Gene ID: | 51513 |
NCBI Accession: | Q9Y603.1 |
UniProt Secondary Accession: | Q9Y603,Q5R3L3, Q5R3L4, Q9NZ65, Q9NZ66, Q9NZ68, Q9NZR8 Q9UNJ7, Q9Y5K4, B3KVC2, B4DVB6, B4E1G4, |
UniProt Related Accession: | Q9Y603 |
Molecular Weight: | 341 |
NCBI Full Name: | Transcription factor ETV7 |
NCBI Synonym Full Names: | ets variant 7 |
NCBI Official Symbol: | ETV7 |
NCBI Official Synonym Symbols: | TEL2; TELB; TEL-2 |
NCBI Protein Information: | transcription factor ETV7; TEL2 oncogene; tel-related Ets factor; ETS-related protein Tel2; ETS translocation variant 7; Ets transcription factor TEL-2b; ets variant gene 7 (TEL2 oncogene) |
UniProt Protein Name: | Transcription factor ETV7 |
UniProt Synonym Protein Names: | ETS translocation variant 7; ETS-related protein Tel2; Tel-related Ets factor; Transcription factor Tel-2 |
Protein Family: | Transcription factor |
UniProt Gene Name: | ETV7 |
UniProt Entry Name: | ETV7_HUMAN |