EREG Antibody (PACO07419)
- SKU:
- PACO07419
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | EREG Antibody (PACO07419) |
抗体コード: | PACO07419 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:10000-1:20000, IHC-p:1:50-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide from human protein at AA range: 71-120 |
憲法: | Liquid |
ストレージバッファ: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
精製方法: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemical analysis of paraffin-embedded Human-liver, antibody was diluted at 1:100. |
シノニム: | Proepiregulin [Cleaved into: Epiregulin (EPR)] |
UniProt Protein Function: | Epiregulin: Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 4q13.3 Cellular Component: extracellular space; integral to plasma membrane; extracellular region Molecular Function:protein binding; growth factor activity; epidermal growth factor receptor binding Biological Process: response to peptide hormone stimulus; nerve growth factor receptor signaling pathway; wound healing; activation of MAPK activity; positive regulation of smooth muscle cell proliferation; positive regulation of interleukin-6 biosynthetic process; female meiosis; negative regulation of smooth muscle cell differentiation; negative regulation of cell proliferation; primary follicle stage, oogenesis; positive regulation of fibroblast proliferation; cell-cell signaling; positive regulation of epidermal growth factor receptor activity; positive regulation of cell proliferation; positive regulation of innate immune response; ovarian cumulus expansion; angiogenesis; negative regulation of epithelial cell proliferation; positive regulation of cytokine production; epidermal growth factor receptor signaling pathway; anatomical structure morphogenesis; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; positive regulation of mitosis; cytokine and chemokine mediated signaling pathway; positive regulation of cytokine biosynthetic process; luteinizing hormone signaling pathway; keratinocyte proliferation; oocyte maturation; keratinocyte differentiation; ovulation; organ morphogenesis; positive regulation of protein kinase activity; mRNA transcription; innate immune response; negative regulation of transcription, DNA-dependent; positive regulation of phosphorylation; positive regulation of DNA replication |
NCBI Summary: | Epiregulin is a member of the epidermal growth factor family. Epiregulin can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. [provided by RefSeq, Jul 2008] |
UniProt Code: | O14944 |
NCBI GenInfo Identifier: | 8134446 |
NCBI Gene ID: | 2069 |
NCBI Accession: | O14944.1 |
UniProt Secondary Accession: | O14944,Q6FH69, B2RC66, |
UniProt Related Accession: | O14944 |
Molecular Weight: | 19,044 Da |
NCBI Full Name: | Proepiregulin |
NCBI Synonym Full Names: | epiregulin |
NCBI Official Symbol: | EREG |
NCBI Official Synonym Symbols: | ER |
NCBI Protein Information: | proepiregulin |
UniProt Protein Name: | Proepiregulin |
Protein Family: | Proepiregulin |
UniProt Gene Name: | EREG |
UniProt Entry Name: | EREG_HUMAN |
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