EPO Antibody (PACO19610)
- SKU:
- PACO19610
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | EPO Antibody (PACO19610) |
抗体コード: | PACO19610 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human EPO |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A549 cells, mouse liver tissue, Primary antibody: PACO19610(EPO Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19610(EPO Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four α helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. |
シノニム: | erythropoietin |
UniProt Protein Function: | EPO: Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Genetic variation in EPO is associated with susceptbility to microvascular complications of diabetes type 2 (MVCD2). These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. Belongs to the EPO/TPO family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: cell surface; extracellular region; extracellular space Molecular Function:erythropoietin receptor binding; protein binding Biological Process: cell proliferation; erythrocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell proliferation; positive regulation of DNA replication; positive regulation of Ras protein signal transduction; positive regulation of transcription, DNA-dependent Disease: Microvascular Complications Of Diabetes, Susceptibility To, 2 |
NCBI Summary: | This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq, Jul 2008] |
UniProt Code: | P01588 |
NCBI GenInfo Identifier: | 119526 |
NCBI Gene ID: | 2056 |
NCBI Accession: | P01588.1 |
UniProt Secondary Accession: | P01588,Q2M2L6, Q549U2, Q9UDZ0, Q9UEZ5, Q9UHA0, |
UniProt Related Accession: | P01588 |
Molecular Weight: | 21kDa |
NCBI Full Name: | Erythropoietin |
NCBI Synonym Full Names: | erythropoietin |
NCBI Official Symbol: | EPO |
NCBI Official Synonym Symbols: | EP; MVCD2 |
NCBI Protein Information: | erythropoietin |
UniProt Protein Name: | Erythropoietin |
UniProt Synonym Protein Names: | INN: Epoetin |
Protein Family: | Erythropoietin |
UniProt Gene Name: | EPO |
Antibodies | ELISA Kits |
Anti-EPO Antibody (CAB12435) | Human EPO (Erythropoietin) CLIA Kit (HUES00064) |
Anti-EPO Antibody (CAB5663) | Human Erythropoietin (EPO) ELISA Kit |
EPO Antibody (PACO09114) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |