ENPP4 Antibody (PACO19603)
- SKU:
- PACO19603
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ENPP4 Antibody (PACO19603) |
抗体コード: | PACO19603 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Synthetic peptide of human ENPP4 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19603(ENPP4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human endometrial cancer tissue, Human placenta tissue, Primary antibody: PACO19603(ENPP4 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19603(ENPP4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | NPP4, also known as ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase family member 4), is a 453 amino acid, single-pass type I membrane protein that belongs to the nucleotide pyrophosphatase/phosphodiesterase family. The gene that encodes NPP4 consists of approximately 16,736 bases and maps to human chromosome 6p21.1. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene, and Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins are also located on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. |
シノニム: | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
UniProt Protein Function: | ENPP4: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. |
UniProt Protein Details: | Protein type:Hydrolase; EC 3.6.1.29; Membrane protein, integral; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 6p21.1 Cellular Component: membrane Molecular Function:bis(5'-adenosyl)-triphosphatase activity Biological Process: positive regulation of blood coagulation; purine ribonucleoside catabolic process |
UniProt Code: | Q9Y6X5 |
NCBI GenInfo Identifier: | 172045555 |
NCBI Gene ID: | 22875 |
NCBI Accession: | Q9Y6X5.3 |
UniProt Secondary Accession: | Q9Y6X5,Q7L2N1, A8K5G1, |
UniProt Related Accession: | Q9Y6X5 |
Molecular Weight: | 51,641 Da |
NCBI Full Name: | Bis(5'-adenosyl)-triphosphatase ENPP4 |
NCBI Synonym Full Names: | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
NCBI Official Symbol: | ENPP4 |
NCBI Official Synonym Symbols: | NPP4 |
NCBI Protein Information: | bis(5'-adenosyl)-triphosphatase ENPP4 |
UniProt Protein Name: | Bis(5'-adenosyl)-triphosphatase ENPP4 |
UniProt Synonym Protein Names: | AP3A hydrolase; AP3Aase; Ectonucleotide pyrophosphatase/phosphodiesterase family member 4; E-NPP 4; NPP-4 |
Protein Family: | Bis(5'-adenosyl)-triphosphatase |
UniProt Gene Name: | ENPP4 |
UniProt Entry Name: | ENPP4_HUMAN |