ELOVL5 Antibody, HRP conjugated (PACO41751)
- SKU:
- PACO41751
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | ELOVL5 Antibody, HRP conjugated (PACO41751) |
抗体コード: | PACO41751 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Elongation of very long chain fatty acid, protein 5 protein (247-299AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acid, elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acid, /VLCFAs per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
シノニム: | Elongation of very long chain fatty acid, protein 5 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL5) (ELOVL fatty acid, elongase 5) (ELOVL FA elongase 5) (Fatty acid, elongase 1) (hELO1) (Very long chain 3-ketoacyl-CoA synthase 5) (Very long chain 3-oxoacyl-CoA synthase 5), ELOVL5, ELOVL2 |
UniProt Protein Function: | ELOVL5: Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. Belongs to the ELO family. |
UniProt Protein Details: | Protein type:EC 2.3.1.199; Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 6p12.1 Cellular Component: cell soma; dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane Molecular Function:fatty acid elongase activity; protein binding Biological Process: cellular lipid metabolic process; linoleic acid metabolic process; triacylglycerol biosynthetic process; unsaturated fatty acid biosynthetic process; unsaturated fatty acid metabolic process; very-long-chain fatty acid biosynthetic process Disease: Spinocerebellar Ataxia 38 |
NCBI Summary: | This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014] |
UniProt Code: | Q9NYP7 |
NCBI GenInfo Identifier: | 74753072 |
NCBI Gene ID: | 60481 |
NCBI Accession: | Q9NYP7.1 |
UniProt Secondary Accession: | Q9NYP7,Q59EL3, Q5TGH5, Q6NXE7, Q7L2S5, Q8NCG4, Q9UI22 B4DZJ2, F6SH78, |
UniProt Related Accession: | Q9NYP7 |
Molecular Weight: | 9,580 Da |
NCBI Full Name: | Elongation of very long chain fatty acids protein 5 |
NCBI Synonym Full Names: | ELOVL fatty acid elongase 5 |
NCBI Official Symbol: | ELOVL5 |
NCBI Official Synonym Symbols: | HELO1; SCA38; dJ483K16.1 |
NCBI Protein Information: | elongation of very long chain fatty acids protein 5 |
UniProt Protein Name: | Elongation of very long chain fatty acids protein 5 |
UniProt Synonym Protein Names: | 3-keto acyl-CoA synthase ELOVL5 |
UniProt Gene Name: | ELOVL5 |
UniProt Entry Name: | ELOV5_HUMAN |