ELMO3 Antibody (PACO53526)
- SKU:
- PACO53526
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ELMO3 Antibody (PACO53526) |
抗体コード: | PACO53526 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Engulfment and cell motility protein 3 protein (464-596AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human melanoma using PACO53526 at dilution of 1:100. | |
Immunofluorescent analysis of MCF-7 cells using PACO53526 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity). |
シノニム: | Engulfment and cell motility protein 3, ELMO3 |
UniProt Protein Function: | ELMO3: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: cytoskeleton; cytoplasm Molecular Function:SH3 domain binding Biological Process: apoptosis; phagocytosis |
NCBI Summary: | The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96BJ8 |
NCBI GenInfo Identifier: | 238054390 |
NCBI Gene ID: | 79767 |
NCBI Accession: | Q96BJ8.3 |
UniProt Secondary Accession: | Q96BJ8,Q9H8A5, B4DV86, |
UniProt Related Accession: | Q96BJ8 |
Molecular Weight: | 720 |
NCBI Full Name: | Engulfment and cell motility protein 3 |
NCBI Synonym Full Names: | engulfment and cell motility 3 |
NCBI Official Symbol: | ELMO3 |
NCBI Official Synonym Symbols: | CED12; CED-12; ELMO-3 |
NCBI Protein Information: | engulfment and cell motility protein 3; ced-12 homolog 3 |
UniProt Protein Name: | Engulfment and cell motility protein 3 |
Protein Family: | Engulfment and cell motility protein |
UniProt Gene Name: | ELMO3 |
UniProt Entry Name: | ELMO3_HUMAN |
Antibodies |
Anti-ELMO3 Antibody (CAB7182) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |