EIF3M Antibody (PACO09050)
- SKU:
- PACO09050
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | EIF3M Antibody (PACO09050) |
抗体コード: | PACO09050 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human EIF3M |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | eukaryotic translation initiation factor 3, subunit M;EIF3M;B5;FLJ29030;GA17;PCID1;hfl-B5 ; |
UniProt Protein Function: | EIF3M: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2). Belongs to the eIF-3 subunit M family. |
UniProt Protein Details: | Protein type:Translation initiation Chromosomal Location of Human Ortholog: 11p13 Cellular Component: eukaryotic translation initiation factor 3 complex Molecular Function:protein binding; translation initiation factor binding; translation initiation factor activity Biological Process: translational initiation; formation of translation preinitiation complex; regulation of translational initiation |
NCBI Summary: | This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q7L2H7 |
NCBI GenInfo Identifier: | 74754296 |
NCBI Gene ID: | 10480 |
NCBI Accession: | Q7L2H7.1 |
UniProt Related Accession: | Q7L2H7 |
Molecular Weight: | Observed: 43 kDaPredicted: 43 kDa |
NCBI Full Name: | Eukaryotic translation initiation factor 3 subunit M |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 3 subunit M |
NCBI Official Symbol: | EIF3M |
NCBI Official Synonym Symbols: | B5; GA17; PCID1; TANGO7; hfl-B5 |
NCBI Protein Information: | eukaryotic translation initiation factor 3 subunit M |
UniProt Protein Name: | Eukaryotic translation initiation factor 3 subunit M |
UniProt Synonym Protein Names: | Fetal lung protein B5; hFL-B5; PCI domain-containing protein 1 |
UniProt Gene Name: | EIF3M |
UniProt Entry Name: | EIF3M_HUMAN |