EHHADH Antibody (PACO16234)
- SKU:
- PACO16234
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | EHHADH Antibody (PACO16234) |
抗体コード: | PACO16234 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Fusion protein of human EHHADH |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO16234(EHHADH Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: PACO16234(EHHADH Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16234(EHHADH Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. |
シノニム: | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
UniProt Protein Function: | EHHADH: 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - lysine degradation; EC 5.3.3.8; Oxidoreductase; EC 4.2.1.17; Other Amino Acids Metabolism - beta-alanine; Lipid Metabolism - fatty acid; EC 1.1.1.35; Mitochondrial; Lyase; Isomerase; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - propanoate Chromosomal Location of Human Ortholog: 3q26.3-q28 Cellular Component: mitochondrion; peroxisome; cytosol Molecular Function:enzyme binding; dodecenoyl-CoA delta-isomerase activity; enoyl-CoA hydratase activity; coenzyme binding; 3-hydroxyacyl-CoA dehydrogenase activity; receptor binding Biological Process: fatty acid beta-oxidation; internal protein amino acid acetylation Disease: Fanconi Renotubular Syndrome 3 |
NCBI Summary: | The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
UniProt Code: | Q08426 |
NCBI GenInfo Identifier: | 223590229 |
NCBI Gene ID: | 1962 |
NCBI Accession: | Q08426.3 |
UniProt Secondary Accession: | Q08426,Q58EZ5, A8K6Y3, B4DWG3, D3DNU0, |
UniProt Related Accession: | Q08426 |
Molecular Weight: | 723 |
NCBI Full Name: | Peroxisomal bifunctional enzyme |
NCBI Synonym Full Names: | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
NCBI Official Symbol: | EHHADH |
NCBI Official Synonym Symbols: | LBP; ECHD; LBFP; PBFE; FRTS3; L-PBE |
NCBI Protein Information: | peroxisomal bifunctional enzyme; PBE; 3,2-trans-enoyl-CoA isomerase; peroxisomal enoyl-CoA hydratase; L-3-hydroxyacyl-CoA dehydrogenase; L-bifunctional protein, peroxisomal; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase |
UniProt Protein Name: | Peroxisomal bifunctional enzyme |
Protein Family: | Peroxisomal bifunctional enzyme |
UniProt Gene Name: | EHHADH |
UniProt Entry Name: | ECHP_HUMAN |