EEF1E1 Antibody, HRP conjugated (PACO26386)
- SKU:
- PACO26386
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | EEF1E1 Antibody, HRP conjugated (PACO26386) |
抗体コード: | PACO26386 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Eukaryotic translation elongation factor 1 epsilon-1 protein (2-174AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Positive modulator of ATM response to DNA damage. |
シノニム: | Eukaryotic translation elongation factor 1 epsilon-1 (Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3) (Elongation factor p18) (Multisynthase complex auxiliary component p18), EEF1E1, AIMP3 P18 |
UniProt Protein Function: | EEF1E1: Positive modulator of ATM response to DNA damage. |
UniProt Protein Details: | Protein type:Translation; Translation elongation Chromosomal Location of Human Ortholog: 6p24.3 Cellular Component: cytoplasm; nucleus; cytosol Molecular Function:protein binding Biological Process: negative regulation of cell proliferation; tRNA aminoacylation for protein translation; positive regulation of apoptosis; gene expression; positive regulation of DNA damage response, signal transduction by p53 class mediator |
NCBI Summary: | This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010] |
UniProt Code: | O43324 |
NCBI GenInfo Identifier: | 17378996 |
NCBI Gene ID: | 9521 |
NCBI Accession: | O43324.1 |
UniProt Related Accession: | O43324 |
Molecular Weight: | 20; 16; 20kDa |
NCBI Full Name: | Eukaryotic translation elongation factor 1 epsilon-1 |
NCBI Synonym Full Names: | eukaryotic translation elongation factor 1 epsilon 1 |
NCBI Official Symbol: | EEF1E1 |
NCBI Official Synonym Symbols: | P18; AIMP3 |
NCBI Protein Information: | eukaryotic translation elongation factor 1 epsilon-1 |
UniProt Protein Name: | Eukaryotic translation elongation factor 1 epsilon-1 |
UniProt Synonym Protein Names: | Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3; Elongation factor p18; Multisynthase complex auxiliary component p18 |
Protein Family: | Eukaryotic translation elongation factor |
UniProt Gene Name: | EEF1E1 |
UniProt Entry Name: | MCA3_HUMAN |