DRAM1 Antibody (PACO50830)
- SKU:
- PACO50830
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DRAM1 Antibody (PACO50830) |
抗体コード: | PACO50830 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human DNA damage-regulated autophagy modulator protein 1 protein (50-100AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human lung cancer using PACO50830 at dilution of 1:100. |
バックグラウンド: | Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy. |
シノニム: | DNA damage-regulated autophagy modulator protein 1 (Damage-regulated autophagy modulator), DRAM1, DRAM |
UniProt Protein Function: | DRAM1: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73- mediated autophagy. Belongs to the DRAM/TMEM150 family. |
UniProt Protein Details: | Protein type:Apoptosis; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 12q23.2 Cellular Component: lysosome; lysosomal membrane; cytoplasm; integral to membrane Biological Process: apoptosis; autophagy; regulation of autophagy |
NCBI Summary: | This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8N682 |
NCBI GenInfo Identifier: | 22450862 |
NCBI Gene ID: | 55332 |
NCBI Accession: | AAH18435 |
UniProt Secondary Accession: | Q8N682,Q7L3E3, Q9NUN1, B7Z4T0, |
UniProt Related Accession: | Q8N682 |
Molecular Weight: | 13,972 Da |
NCBI Full Name: | Damage-regulated autophagy modulator |
NCBI Synonym Full Names: | DNA-damage regulated autophagy modulator 1 |
NCBI Official Symbol: | DRAM1 |
NCBI Official Synonym Symbols: | DRAM |
NCBI Protein Information: | DNA damage-regulated autophagy modulator protein 1 |
UniProt Protein Name: | DNA damage-regulated autophagy modulator protein 1 |
UniProt Synonym Protein Names: | Damage-regulated autophagy modulator |
UniProt Gene Name: | DRAM1 |
UniProt Entry Name: | DRAM1_HUMAN |
Antibodies | ELISA Kits |
Anti-DRAM1 Antibody (CAB15468) | Human DRAM1 ELISA Kit |
Human DNA damage-regulated autophagy modulator protein 1 (DRAM1) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |