DIDO1 Antibody (PACO43273)
- SKU:
- PACO43273
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DIDO1 Antibody (PACO43273) |
抗体コード: | PACO43273 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Death-inducer obliterator 1 protein (1-300AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO43273 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO43273 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO43273 at dilution of 1:100. |
バックグラウンド: | Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development. Isoform 2: Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes. |
シノニム: | Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1), DIDO1, C20orf158 DATF1 KIAA0333 |
UniProt Protein Function: | DATF1: Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Ubiquitous. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor Chromosomal Location of Human Ortholog: 20q13.33 Cellular Component: cytoplasm; spindle; nucleus Molecular Function:zinc ion binding Biological Process: transcription, DNA-dependent |
NCBI Summary: | Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9BTC0 |
NCBI GenInfo Identifier: | 116241332 |
NCBI Gene ID: | 11083 |
NCBI Accession: | Q9BTC0.5 |
UniProt Secondary Accession: | Q9BTC0,O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q4VXV8 Q4VXV9, Q96D72, A8MY65, B9EH82, E1P5I1, |
UniProt Related Accession: | Q9BTC0 |
Molecular Weight: | 2240 |
NCBI Full Name: | Death-inducer obliterator 1 |
NCBI Synonym Full Names: | death inducer-obliterator 1 |
NCBI Official Symbol: | DIDO1 |
NCBI Official Synonym Symbols: | BYE1; DIO1; DATF1; DIDO2; DIDO3; DIO-1; DATF-1; C20orf158; dJ885L7.8 |
NCBI Protein Information: | death-inducer obliterator 1; death-associated transcription factor 1 |
UniProt Protein Name: | Death-inducer obliterator 1 |
UniProt Synonym Protein Names: | Death-associated transcription factor 1; DATF-1 |
Protein Family: | Death-inducer obliterator |
UniProt Gene Name: | DIDO1 |
UniProt Entry Name: | DIDO1_HUMAN |