DCUN1D1 Antibody, HRP conjugated (PACO38723)
- SKU:
- PACO38723
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | DCUN1D1 Antibody, HRP conjugated (PACO38723) |
抗体コード: | PACO38723 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human DCN1-like protein 1 protein (1-259AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. |
シノニム: | DCN1-like protein 1 (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene), DCUN1D1, DCUN1L1 RP42 SCCRO |
UniProt Protein Function: | DCUN1D1: Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. |
UniProt Protein Details: | Protein type:Oncoprotein; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 3q26.3 Cellular Component: nucleus; ubiquitin ligase complex Molecular Function:protein binding; small conjugating protein binding; ubiquitin conjugating enzyme binding Biological Process: positive regulation of ubiquitin-protein ligase activity; protein neddylation |
UniProt Code: | Q96GG9 |
NCBI GenInfo Identifier: | 809281410 |
NCBI Gene ID: | 54165 |
NCBI Accession: | NP_001295030.1 |
UniProt Secondary Accession: | Q96GG9,Q7L3G9, Q8TEX7, Q9H6M1, Q9HCT3, B2RB37, |
UniProt Related Accession: | Q96GG9 |
Molecular Weight: | 30,124 Da |
NCBI Full Name: | DCN1-like protein 1 isoform 2 |
NCBI Synonym Full Names: | defective in cullin neddylation 1 domain containing 1 |
NCBI Official Symbol: | DCUN1D1 |
NCBI Official Synonym Symbols: | RP42; SCRO; Tes3; DCNL1; SCCRO; DCUN1L1 |
NCBI Protein Information: | DCN1-like protein 1 |
UniProt Protein Name: | DCN1-like protein 1 |
UniProt Synonym Protein Names: | DCUN1 domain-containing protein 1; Defective in cullin neddylation protein 1-like protein 1; Squamous cell carcinoma-related oncogene |
Protein Family: | DCN1-like protein |
UniProt Gene Name: | DCUN1D1 |
UniProt Entry Name: | DCNL1_HUMAN |