DCTD Antibody (PACO44476)
- SKU:
- PACO44476
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DCTD Antibody (PACO44476) |
抗体コード: | PACO44476 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Deoxycytidylate deaminase protein (1-178AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO44476 at dilution of 1:100. |
バックグラウンド: | Supplies the nucleotide substrate for thymidylate synthetase. |
シノニム: | Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase), DCTD |
UniProt Protein Function: | DCTD: catalyzes the deamination of dCMP to dUMP, thus providing the nucleotide substrate for thymidylate synthase. Allosteric enzyme whose activity is greatly influenced by the end products of its metabolic pathway, dCTP and dTTP. |
UniProt Protein Details: | Protein type:Nucleotide Metabolism - pyrimidine; EC 3.5.4.12; Hydrolase Chromosomal Location of Human Ortholog: 4q35.1 Cellular Component: cytosol Molecular Function:zinc ion binding; dCMP deaminase activity Biological Process: pyrimidine base metabolic process; nucleobase, nucleoside and nucleotide metabolic process; nucleotide biosynthetic process; pyrimidine nucleotide metabolic process; pyrimidine nucleoside biosynthetic process |
NCBI Summary: | The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P32321 |
NCBI GenInfo Identifier: | 23503055 |
NCBI Gene ID: | 1635 |
NCBI Accession: | P32321.2 |
UniProt Secondary Accession: | P32321,Q5M7Z8, Q9BVD8, B2R836, D3DP49, D3DP50, |
UniProt Related Accession: | P32321 |
Molecular Weight: | 178 |
NCBI Full Name: | Deoxycytidylate deaminase |
NCBI Synonym Full Names: | dCMP deaminase |
NCBI Official Symbol: | DCTD |
NCBI Protein Information: | deoxycytidylate deaminase |
UniProt Protein Name: | Deoxycytidylate deaminase |
UniProt Synonym Protein Names: | dCMP deaminase |
Protein Family: | Deoxycytidylate deaminase |
UniProt Gene Name: | DCTD |
UniProt Entry Name: | DCTD_HUMAN |