CXCR5 Antibody (PACO17755)
- SKU:
- PACO17755
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CXCR5 Antibody (PACO17755) |
抗体コード: | PACO17755 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:10000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Synthetic peptide of human CXCR5 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human rectal cancer tissue using PACO17755(CXCR5 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
シノニム: | chemokine (C-X-C motif) receptor 5 |
UniProt Protein Function: | CXCR5: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane Molecular Function:G-protein coupled receptor activity; protein binding; C-X-C chemokine receptor activity Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; B cell activation; immune response; cell motility; chemotaxis; lymph node development |
NCBI Summary: | This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] |
UniProt Code: | P32302 |
NCBI GenInfo Identifier: | 416718 |
NCBI Gene ID: | 643 |
NCBI Accession: | P32302.1 |
UniProt Related Accession: | P32302 |
Molecular Weight: | |
NCBI Full Name: | C-X-C chemokine receptor type 5 |
NCBI Synonym Full Names: | C-X-C motif chemokine receptor 5 |
NCBI Official Symbol: | CXCR5 |
NCBI Official Synonym Symbols: | BLR1; CD185; MDR15 |
NCBI Protein Information: | C-X-C chemokine receptor type 5 |
UniProt Protein Name: | C-X-C chemokine receptor type 5 |
UniProt Synonym Protein Names: | Burkitt lymphoma receptor 1; Monocyte-derived receptor 15; MDR-15; CD_antigen: CD185 |
UniProt Gene Name: | CXCR5 |
UniProt Entry Name: | CXCR5_HUMAN |
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