CTNNBIP1 Antibody (PACO43362)
- SKU:
- PACO43362
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | CTNNBIP1 Antibody (PACO43362) |
抗体コード: | PACO43362 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Beta-catenin-interacting protein 1 protein (1-81AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
バックグラウンド: | Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. |
シノニム: | Beta-catenin-interacting protein 1 (Inhibitor of beta-catenin and Tcf-4), CTNNBIP1, ICAT |
UniProt Protein Function: | CTNNBIP1: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. Belongs to the CTNNBIP1 family. |
UniProt Protein Details: | Protein type:Cell development/differentiation; Inhibitor Chromosomal Location of Human Ortholog: 1p36.22 Cellular Component: nucleoplasm; cytoplasm; nucleus; beta-catenin destruction complex; cytosol Molecular Function:protein binding; beta-catenin binding Biological Process: anterior/posterior pattern formation; positive regulation of monocyte differentiation; positive regulation of osteoblast differentiation; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud branching; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; negative regulation of protein binding; regulation of vascular permeability during acute inflammatory response; negative regulation of DNA binding |
NCBI Summary: | The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NSA3 |
NCBI GenInfo Identifier: | 59889555 |
NCBI Gene ID: | 56998 |
NCBI Accession: | NP_001012329.1 |
UniProt Secondary Accession: | Q9NSA3,Q9JJN6, |
UniProt Related Accession: | Q9NSA3 |
Molecular Weight: | 9,170 Da |
NCBI Full Name: | beta-catenin-interacting protein 1 |
NCBI Synonym Full Names: | catenin, beta interacting protein 1 |
NCBI Official Symbol: | CTNNBIP1 |
NCBI Official Synonym Symbols: | ICAT |
NCBI Protein Information: | beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; inhibitor of beta-catenin and Tcf-4 |
UniProt Protein Name: | Beta-catenin-interacting protein 1 |
UniProt Synonym Protein Names: | Inhibitor of beta-catenin and Tcf-4 |
UniProt Gene Name: | CTNNBIP1 |
UniProt Entry Name: | CNBP1_HUMAN |