CSNK1A1 Antibody (PACO25993)
- SKU:
- PACO25993
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | CSNK1A1 Antibody (PACO25993) |
抗体コード: | PACO25993 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Casein kinase I isoform α protein (2-337AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human skin tissue using PACO25993 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO25993 at dilution of 1:100. |
バックグラウンド: | Casein kinases are operationally defined by their preferential utilization of acid, c proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis. |
シノニム: | Casein kinase I isoform α (CKI-alpha) (EC 2.7.11.1) (CK1), CSNK1A1 |
UniProt Protein Function: | CK1A: an ubiquitous protein kinase of the CK1 family. Participates in Wnt signaling. Phosphorylates beta catenin, marking it for beta-TRCp-mediated ubiquitinylation and proteasomal degradation. |
UniProt Protein Details: | Protein type:Protein kinase, CK1; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CK1 group; CK1 family Chromosomal Location of Human Ortholog: 5q32 Cellular Component: beta-catenin destruction complex; centrosome; cytosol; keratin filament; membrane; mRNA cleavage and polyadenylation specificity factor complex; nuclear speck Molecular Function:kinase activity; protein binding; protein kinase activity; protein serine/threonine kinase activity Biological Process: cell surface receptor linked signal transduction; Golgi organization and biogenesis; intermediate filament cytoskeleton organization and biogenesis; peptidyl-serine phosphorylation; phagocytosis; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; protein amino acid phosphorylation; regulation of cell shape; Wnt receptor signaling pathway |
UniProt Code: | P48729 |
NCBI GenInfo Identifier: | 31077177 |
NCBI Gene ID: | 1452 |
NCBI Accession: | P48729.2 |
UniProt Secondary Accession: | P48729,Q4JJA0, Q5U046, Q5U047, Q6FGA2, Q71TU5, Q96HD2 Q9UDK3, D3DQG0, D3DQG1, |
UniProt Related Accession: | P48729 |
Molecular Weight: | 37,567 Da |
NCBI Full Name: | Casein kinase I isoform alpha |
NCBI Synonym Full Names: | casein kinase 1 alpha 1 |
NCBI Official Symbol: | CSNK1A1 |
NCBI Official Synonym Symbols: | CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p |
NCBI Protein Information: | casein kinase I isoform alpha |
UniProt Protein Name: | Casein kinase I isoform alpha |
UniProt Synonym Protein Names: | CK1 |
Protein Family: | Casein kinase |
UniProt Gene Name: | CSNK1A1 |
UniProt Entry Name: | KC1A_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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