CLTC Antibody (PACO19479)
- SKU:
- PACO19479
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | CLTC Antibody (PACO19479) |
抗体コード: | PACO19479 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human CLTC |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19479(CLTC Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: NIH/3T3 cells, hela cells, Primary antibody: PACO19479(CLTC Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19479(CLTC Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. |
シノニム: | clathrin, heavy chain (Hc) |
UniProt Protein Function: | CLTC: a major protein component of the cytoplasmic face of coated vesicles and coated pits. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Vesicle Chromosomal Location of Human Ortholog: 17q23.1 Cellular Component: clathrin coat; clathrin-coated vesicle; cytosol; endosome; extracellular matrix; focal adhesion; lysosome; membrane; plasma membrane; protein complex; spindle; trans-Golgi network membrane Molecular Function:clathrin light chain binding; double-stranded RNA binding; protein binding; protein kinase binding; RNA binding Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; clathrin cage assembly; microtubule-based movement; mitotic cell cycle; osteoblast differentiation; receptor internalization; receptor-mediated endocytosis; retrograde transport, endosome to Golgi; transferrin transport; Wnt receptor signaling pathway, planar cell polarity pathway |
NCBI Summary: | Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q00610 |
NCBI GenInfo Identifier: | 1705916 |
NCBI Gene ID: | 1213 |
NCBI Accession: | Q00610.5 |
UniProt Secondary Accession: | Q00610,Q6N0A0, Q86TF2, D3DU00, |
UniProt Related Accession: | Q00610 |
Molecular Weight: | 192kDa |
NCBI Full Name: | Clathrin heavy chain 1 |
NCBI Synonym Full Names: | clathrin heavy chain |
NCBI Official Symbol: | CLTC |
NCBI Official Synonym Symbols: | Hc; CHC; CHC17; CLH-17; CLTCL2 |
NCBI Protein Information: | clathrin heavy chain 1 |
UniProt Protein Name: | Clathrin heavy chain 1 |
UniProt Synonym Protein Names: | Clathrin heavy chain on chromosome 17; CLH-17 |
Protein Family: | Clathrin |
UniProt Gene Name: | CLTC |