CLPB Antibody, HRP conjugated (PACO41883)
- SKU:
- PACO41883
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | CLPB Antibody, HRP conjugated (PACO41883) |
抗体コード: | PACO41883 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Caseinolytic peptidase B protein homolog protein (1-350AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | May function as a regulatory ATPase and be related to secretion/protein trafficking process. |
シノニム: | Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3), CLPB, HSP78 SKD3 |
UniProt Protein Function: | CLPB: May function as a regulatory ATPase and be related to secretion/protein trafficking process. Belongs to the clpA/clpB family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 11q13.4 Molecular Function:protein binding Disease: 3-methylglutaconic Aciduria With Cataracts, Neurologic Involvement, And Neutropenia |
NCBI Summary: | This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] |
UniProt Code: | Q9H078 |
NCBI GenInfo Identifier: | 25009267 |
NCBI Gene ID: | 81570 |
NCBI Accession: | Q9H078.1 |
UniProt Secondary Accession: | Q9H078,Q8ND11, Q9H8Y0, B4DXJ7, B4DXP7, B4DXW4, E7EWN6 F8W7P6, |
UniProt Related Accession: | Q9H078 |
Molecular Weight: | 57,664 Da |
NCBI Full Name: | Caseinolytic peptidase B protein homolog |
NCBI Synonym Full Names: | ClpB homolog, mitochondrial AAA ATPase chaperonin |
NCBI Official Symbol: | CLPB |
NCBI Official Synonym Symbols: | SKD3; HSP78; MGCA7; ANKCLB; MEGCANN |
NCBI Protein Information: | caseinolytic peptidase B protein homolog |
UniProt Protein Name: | Caseinolytic peptidase B protein homolog |
UniProt Synonym Protein Names: | Suppressor of potassium transport defect 3 |
Protein Family: | Chaperone protein |
UniProt Gene Name: | CLPB |
UniProt Entry Name: | CLPB_HUMAN |