CKMT2 Antibody (PACO16041)
- SKU:
- PACO16041
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CKMT2 Antibody (PACO16041) |
抗体コード: | PACO16041 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human CKMT2 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16041(CKMT2 Antibody) at dilution 1/60. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: PACO16041(CKMT2 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO16041(CKMT2 Antibody) at dilution 1/60. (Original magnification: x200). |
バックグラウンド: | Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. |
シノニム: | creatine kinase, mitochondrial 2 (sarcomeric) |
UniProt Protein Function: | CKMT2: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family. |
UniProt Protein Details: | Protein type:Mitochondrial; Amino Acid Metabolism - arginine and proline; Kinase, other; EC 2.7.3.2 Chromosomal Location of Human Ortholog: 5q13.3 Cellular Component: mitochondrial inner membrane; mitochondrion Molecular Function:creatine kinase activity Biological Process: creatine metabolic process; muscle contraction |
NCBI Summary: | Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P17540 |
NCBI GenInfo Identifier: | 116242603 |
NCBI Gene ID: | 1160 |
NCBI Accession: | P17540.2 |
UniProt Secondary Accession: | P17540,Q6ICS8, Q8N1E1, |
UniProt Related Accession: | P17540 |
Molecular Weight: | 47,504 Da |
NCBI Full Name: | Creatine kinase S-type, mitochondrial |
NCBI Synonym Full Names: | creatine kinase, mitochondrial 2 |
NCBI Official Symbol: | CKMT2 |
NCBI Official Synonym Symbols: | SMTCK |
NCBI Protein Information: | creatine kinase S-type, mitochondrial |
UniProt Protein Name: | Creatine kinase S-type, mitochondrial |
UniProt Synonym Protein Names: | Basic-type mitochondrial creatine kinase; Mib-CK; Sarcomeric mitochondrial creatine kinase; S-MtCK |
Protein Family: | Creatine kinase |
UniProt Gene Name: | CKMT2 |
UniProt Entry Name: | KCRS_HUMAN |
Antibodies | ELISA Kits |
Anti-CKMT2 Antibody (CAB2206) | CKMT2 Colorimetric Cell-Based ELISA |
Anti-CKMT2 Antibody (CAB8088) | |
CKMT2 Antibody (PACO01517) | |
CKMT2 Antibody (PACO08448) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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