CEP63 Antibody (PACO08367)
- SKU:
- PACO08367
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CEP63 Antibody (PACO08367) |
抗体コード: | PACO08367 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human CEP63 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | centrosomal protein 63kDa;CEP63;FLJ13386;MGC78416 ; |
UniProt Protein Function: | Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned (PubMed:21983783, PubMed:26297806). Also recruits CDK1 to centrosomes (PubMed:21406398). Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (PubMed:21406398). |
NCBI Summary: | This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96MT8 |
NCBI GenInfo Identifier: | 56748851 |
NCBI Gene ID: | 80254 |
NCBI Accession: | Q96MT8.1 |
UniProt Secondary Accession: | Q96MT8,Q96CR0, Q9H8F5, Q9H8N0, D3DND8, D3DND9, D3DNE0 |
UniProt Related Accession: | Q96MT8 |
Molecular Weight: | 55,591 Da |
NCBI Full Name: | Centrosomal protein of 63 kDa |
NCBI Synonym Full Names: | centrosomal protein 63 |
NCBI Official Symbol: | CEP63 |
NCBI Official Synonym Symbols: | SCKL6 |
NCBI Protein Information: | centrosomal protein of 63 kDa |
UniProt Protein Name: | Centrosomal protein of 63 kDa |
Protein Family: | Centrosomal protein |
UniProt Gene Name: | CEP63 |
UniProt Entry Name: | CEP63_HUMAN |