CDC37 Antibody (PACO06336)
- SKU:
- PACO06336
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CDC37 Antibody (PACO06336) |
抗体コード: | PACO06336 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthesized peptide derived from the Internal region of human Cdc37. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot analysis of various cells using Cdc37 Polyclonal Antibody. | |
Western Blot analysis of 3T3 cells using Cdc37 Polyclonal Antibody. |
シノニム: | CDC37; CDC37A; Hsp90 co-chaperone Cdc37; Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37 |
UniProt Protein Function: | CDC37: a molecular chaperone that functions in cell signal transduction. Forms complexes with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. Also interacts with androgen receptor. It is thought to play a critical role in directing Hsp90 to its target kinases. |
UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: protein complex; cytoplasm; cytosol Molecular Function:protein kinase B binding; protein binding; chaperone binding; heat shock protein binding; unfolded protein binding; mitogen-activated protein kinase kinase kinase binding; Hsp90 protein binding; kinase binding Biological Process: protein folding; protein stabilization; regulation of cyclin-dependent protein kinase activity; protein targeting |
NCBI Summary: | The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q16543 |
NCBI GenInfo Identifier: | 21542000 |
NCBI Gene ID: | 11140 |
NCBI Accession: | Q16543.1 |
UniProt Secondary Accession: | Q16543,Q53YA2, |
UniProt Related Accession: | Q16543 |
Molecular Weight: | 378 |
NCBI Full Name: | Hsp90 co-chaperone Cdc37 |
NCBI Synonym Full Names: | cell division cycle 37 |
NCBI Official Symbol: | CDC37 |
NCBI Official Synonym Symbols: | P50CDC37 |
NCBI Protein Information: | hsp90 co-chaperone Cdc37; cell division cycle 37 homolog; CDC37 cell division cycle 37 homolog; hsp90 chaperone protein kinase-targeting subunit; CDC37 (cell division cycle 37, S. cerevisiae, homolog) |
UniProt Protein Name: | Hsp90 co-chaperone Cdc37 |
UniProt Synonym Protein Names: | Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37Hsp90 co-chaperone Cdc37, N-terminally processed |
Protein Family: | Hsp90 co-chaperone |
UniProt Gene Name: | CDC37 |
UniProt Entry Name: | CDC37_HUMAN |
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