CD84 Antibody (PACO01961)
- SKU:
- PACO01961
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CD84 Antibody |
抗体コード: | PACO01961 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human, Mouse |
免疫原: | synthesized peptide derived from the Internal region of human CD84. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | CD84; SLAMF5; SLAM family member 5; Cell surface antigen MAX.3; Hly9-beta; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; CD84 |
UniProt Protein Function: | CD84: Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain- containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells. 7 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Immunoglobulin superfamily; Motility/polarity/chemotaxis; Cell surface Chromosomal Location of Human Ortholog: 1q24 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:protein binding Biological Process: adaptive immune response; blood coagulation; defense response; homophilic cell adhesion; innate immune response; leukocyte migration; negative regulation of granulocyte macrophage colony-stimulating factor production; negative regulation of interleukin-18 production; negative regulation of mast cell activation; negative regulation of mast cell degranulation |
NCBI Summary: | This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily. The encoded protein is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011] |
UniProt Code: | Q9UIB8 |
NCBI GenInfo Identifier: | 74762772 |
NCBI Gene ID: | 8832 |
NCBI Accession: | Q9UIB8.1 |
UniProt Secondary Accession: | Q9UIB8,O15430, O95266, O95660, Q5H9R1, Q6FHA8, Q8WLP1 Q8WWI8, Q9UF04, Q9UIB6, B2R8T1, B7Z3R8, |
UniProt Related Accession: | Q9UIB8 |
Molecular Weight: | 24,025 Da |
NCBI Full Name: | SLAM family member 5 |
NCBI Synonym Full Names: | CD84 molecule |
NCBI Official Symbol: | CD84 |
NCBI Official Synonym Symbols: | LY9B; hCD84; mCD84; SLAMF5 |
NCBI Protein Information: | SLAM family member 5 |
UniProt Protein Name: | SLAM family member 5 |
UniProt Synonym Protein Names: | Cell surface antigen MAX.3; Hly9-beta; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; CD_antigen: CD84 |
Protein Family: | SLAM family |
UniProt Gene Name: | CD84 |
UniProt Entry Name: | SLAF5_HUMAN |