CD38 Antibody (PACO02078)
- SKU:
- PACO02078
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | CD38 Antibody |
抗体コード: | PACO02078 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human |
免疫原: | synthesized peptide derived from the Internal region of human CD38. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | CD38; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD38 |
UniProt Protein Function: | CD38: Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. Belongs to the ADP-ribosyl cyclase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.2.2.6; EC 2.4.99.20; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Hydrolase; Cell surface; Apoptosis; Lyase; Membrane protein, integral; Cell cycle regulation Chromosomal Location of Human Ortholog: 4p15 Cellular Component: cell surface; membrane; integral to membrane; plasma membrane; nucleus Molecular Function:transferase activity; phosphorus-oxygen lyase activity; NAD+ nucleosidase activity; NAD(P)+ nucleosidase activity Biological Process: response to drug; response to retinoic acid; metabolic process; positive regulation of transcription, DNA-dependent; positive regulation of insulin secretion; female pregnancy; signal transduction; positive regulation of cell growth; response to estradiol stimulus; B cell receptor signaling pathway; elevation of cytosolic calcium ion concentration; response to hydroperoxide; positive regulation of B cell proliferation; positive regulation of vasoconstriction; response to hypoxia; response to progesterone stimulus; negative regulation of transcription, DNA-dependent; negative regulation of bone resorption; negative regulation of apoptosis |
NCBI Summary: | CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling. [provided by RefSeq, Jul 2008] |
UniProt Code: | P28907 |
NCBI GenInfo Identifier: | 55977782 |
NCBI Gene ID: | 952 |
NCBI Accession: | P28907.2 |
UniProt Secondary Accession: | P28907,O00121, O00122, Q96HY4, |
UniProt Related Accession: | P28907 |
Molecular Weight: | 300 |
NCBI Full Name: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
NCBI Synonym Full Names: | CD38 molecule |
NCBI Official Symbol: | CD38 |
NCBI Official Synonym Symbols: | T10; ADPRC 1 |
NCBI Protein Information: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; CD38 antigen (p45); NAD(+) nucleosidase; ADP-ribosyl cyclase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase |
UniProt Protein Name: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
UniProt Synonym Protein Names: | 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (EC:2.4.99.20); 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADPRC 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD_antigen: CD38 |
Protein Family: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase |
UniProt Gene Name: | CD38 |
UniProt Entry Name: | CD38_HUMAN |