CD27 Antibody, HRP conjugated (PACO32561)
- SKU:
- PACO32561
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | CD27 Antibody, HRP conjugated (PACO32561) |
抗体コード: | PACO32561 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human CD27 antigen protein (20-191AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. |
シノニム: | CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27), CD27, TNFRSF7 |
UniProt Protein Function: | CD27: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Apoptosis; Receptor, cytokine Chromosomal Location of Human Ortholog: 12p13 Cellular Component: integral to plasma membrane; neuron projection; nucleus; plasma membrane Molecular Function:caspase inhibitor activity; protein binding; tumor necrosis factor receptor activity Biological Process: brain development; immune response; induction of apoptosis via death domain receptors; inflammatory response; negative regulation of apoptosis; positive regulation of JNK cascade; positive regulation of MAPKKK cascade; regulation of cell proliferation; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway Disease: Lymphoproliferative Syndrome 2 |
NCBI Summary: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] |
UniProt Code: | P26842 |
NCBI GenInfo Identifier: | 269849546 |
NCBI Gene ID: | 939 |
NCBI Accession: | P26842.2 |
UniProt Secondary Accession: | P26842,B2RDZ0, |
UniProt Related Accession: | P26842 |
Molecular Weight: | 29,137 Da |
NCBI Full Name: | CD27 antigen |
NCBI Synonym Full Names: | CD27 molecule |
NCBI Official Symbol: | CD27 |
NCBI Official Synonym Symbols: | T14; S152; Tp55; TNFRSF7; S152. LPFS2 |
NCBI Protein Information: | CD27 antigen |
UniProt Protein Name: | CD27 antigen |
UniProt Synonym Protein Names: | CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; CD_antigen: CD27 |
Protein Family: | CD27 antigen |
UniProt Gene Name: | CD27 |
UniProt Entry Name: | CD27_HUMAN |