CD177 Antibody, HRP conjugated (PACO39655)
- SKU:
- PACO39655
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | CD177 Antibody, HRP conjugated (PACO39655) |
抗体コード: | PACO39655 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human CD177 antigen protein (22-321AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | extracellular exosome, plasma membrane, blood coagulation, leukocyte migration |
シノニム: | CD177 antigen (Human neutrophil alloantigen 2a) (HNA-2a) (NB1 glycoprotein) (NB1 GP) (Polycythemia rubra vera protein 1) (PRV-1) (CD antigen CD177), CD177, NB1 PRV1 |
UniProt Protein Function: | CD177: Induced by CSF3 in resting granulocytes. Induced in patients with polycythemia vera (PV) and with essential thrombocythemia (ET). 3 isoforms of the human protein are produced by alternative splicing |
UniProt Protein Details: | Protein type:Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: plasma membrane Biological Process: blood coagulation; leukocyte migration |
NCBI Summary: | This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014] |
UniProt Code: | Q8N6Q3 |
NCBI GenInfo Identifier: | 91208246 |
NCBI Gene ID: | 57126 |
NCBI Accession: | Q8N6Q3.2 |
UniProt Secondary Accession: | Q8N6Q3,Q711Q2, Q8NCV9, Q96QH1, Q9HDA5, |
UniProt Related Accession: | Q8N6Q3 |
Molecular Weight: | 437 |
NCBI Full Name: | CD177 antigen |
NCBI Synonym Full Names: | CD177 molecule |
NCBI Official Symbol: | CD177 |
NCBI Official Synonym Symbols: | NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP |
NCBI Protein Information: | CD177 antigen; NB1 glycoprotein; cell surface receptor; human neutrophil alloantigen 2a; polycythemia rubra vera protein 1 |
UniProt Protein Name: | CD177 antigen |
UniProt Synonym Protein Names: | Human neutrophil alloantigen 2a; HNA-2a; NB1 glycoprotein; NB1 GP; Polycythemia rubra vera protein 1; PRV-1; CD_antigen: CD177 |
Protein Family: | CD177 antigen |
UniProt Gene Name: | CD177 |
UniProt Entry Name: | CD177_HUMAN |