CD151 Antibody (PACO48270)
- SKU:
- PACO48270
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CD151 Antibody (PACO48270) |
抗体コード: | PACO48270 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human CD151 antigen protein (125-199AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Mouse liver tissue. All lanes: CD151 antibody at 2.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 29 kDa. Observed band size: 29 kDa.. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO48270 at dilution of 1:100. | |
Immunofluorescent analysis of A549 cells using PACO48270 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. |
シノニム: | CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151), CD151, TSPAN24 |
UniProt Protein Function: | CD151: Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. Defects in CD151 are the cause of nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD). NPEBD is characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor. Belongs to the tetraspanin (TM4SF) family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: focal adhesion; membrane; integral to plasma membrane; plasma membrane; cytosol Molecular Function:integrin binding; protein binding Biological Process: T cell proliferation; cell migration; hemidesmosome assembly; extracellular matrix organization and biogenesis; cell adhesion Disease: Raph Blood Group System; Nephropathy With Pretibial Epidermolysis Bullosa And Deafness |
NCBI Summary: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P48509 |
NCBI GenInfo Identifier: | 85687560 |
NCBI Gene ID: | 977 |
NCBI Accession: | P48509.3 |
UniProt Secondary Accession: | P48509,Q14826, Q86U54, Q96TE3, A8KAK8, E9PI15, |
UniProt Related Accession: | P48509 |
Molecular Weight: | 253 |
NCBI Full Name: | CD151 antigen |
NCBI Synonym Full Names: | CD151 molecule (Raph blood group) |
NCBI Official Symbol: | CD151 |
NCBI Official Synonym Symbols: | GP27; MER2; RAPH; SFA1; PETA-3; TSPAN24 |
NCBI Protein Information: | CD151 antigen; tspan-24; tetraspanin-24; membrane glycoprotein SFA-1; CD151 antigen (Raph blood group); hemidesmosomal tetraspanin CD151; platelet surface glycoprotein gp27; platelet-endothelial tetraspan antigen 3; platelet-endothelial cell tetraspan antigen 3 |
UniProt Protein Name: | CD151 antigen |
UniProt Synonym Protein Names: | GP27; Membrane glycoprotein SFA-1; Platelet-endothelial tetraspan antigen 3; PETA-3; Tetraspanin-24; Tspan-24; CD_antigen: CD151 |
Protein Family: | CD151 antigen |
UniProt Gene Name: | CD151 |
UniProt Entry Name: | CD151_HUMAN |