C9 Antibody, HRP conjugated (PACO45707)
- SKU:
- PACO45707
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | C9 Antibody, HRP conjugated (PACO45707) |
抗体コード: | PACO45707 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Complement component C9 protein (74-155AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. |
シノニム: | Complement component C9 [Cleaved into: Complement component C9a; Complement component C9b], C9 |
UniProt Protein Function: | C9: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. Defects in C9 are a cause of complement component 9 deficiency (C9D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family. |
UniProt Protein Details: | Protein type:Extracellular matrix; Membrane protein, multi-pass; Membrane protein, integral; Apoptosis Chromosomal Location of Human Ortholog: 5p14-p12 Cellular Component: membrane attack complex; integral to plasma membrane; cytoplasm; plasma membrane; extracellular region Biological Process: complement activation, alternative pathway; regulation of complement activation; innate immune response; hemolysis by symbiont of host red blood cells; complement activation, classical pathway Disease: Macular Degeneration, Age-related, 15; Complement Component 9 Deficiency |
NCBI Summary: | This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009] |
UniProt Code: | P02748 |
NCBI GenInfo Identifier: | 1352108 |
NCBI Gene ID: | 735 |
NCBI Accession: | P02748.2 |
UniProt Related Accession: | P02748 |
Molecular Weight: | |
NCBI Full Name: | Complement component C9 |
NCBI Synonym Full Names: | complement component 9 |
NCBI Official Symbol: | C9 |
NCBI Official Synonym Symbols: | C9D; ARMD15 |
NCBI Protein Information: | complement component C9 |
UniProt Protein Name: | Complement component C9 |
Protein Family: | Complement component |
UniProt Gene Name: | C9 |
UniProt Entry Name: | CO9_HUMAN |