BTN3A1 Antibody (PACO25288)
- SKU:
- PACO25288
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | BTN3A1 Antibody (PACO25288) |
抗体コード: | PACO25288 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Butyrophilin subfamily 3 member A1 protein (30-254AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: BTN3A1 antibody at 12µg/ml + Mouse liver tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 58, 40, 42, 53 kDa Observed band size: 58 kDa . | |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO25288 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO25288 at dilution of 1:100. |
バックグラウンド: | Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. |
シノニム: | Butyrophilin subfamily 3 member A1 (CD antigen CD277), BTN3A1, BTF5 |
UniProt Protein Function: | Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. |
NCBI Summary: | The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010] |
UniProt Code: | O00481 |
NCBI GenInfo Identifier: | 117949374 |
NCBI Gene ID: | 11119 |
NCBI Accession: | O00481.3 |
UniProt Secondary Accession: | O00481,Q0P515, Q147X5, Q53F15, Q99420, Q9HCY1, A2A278 A8K2C8, B4DIQ1, B4DRM2, E9PGB4, E9PHG8, |
UniProt Related Accession: | O00481 |
Molecular Weight: | 52,019 Da |
NCBI Full Name: | Butyrophilin subfamily 3 member A1 |
NCBI Synonym Full Names: | butyrophilin subfamily 3 member A1 |
NCBI Official Symbol: | BTN3A1 |
NCBI Official Synonym Symbols: | BTF5; BT3.1; CD277; BTN3.1 |
NCBI Protein Information: | butyrophilin subfamily 3 member A1 |
UniProt Protein Name: | Butyrophilin subfamily 3 member A1 |
UniProt Synonym Protein Names: | CD_antigen: CD277 |
UniProt Gene Name: | BTN3A1 |
Antibodies |
Anti-BTN3A1 Antibody (CAB10288) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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