BLK Antibody (PACO15874)
- SKU:
- PACO15874
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | BLK Antibody (PACO15874) |
抗体コード: | PACO15874 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse |
免疫原: | Fusion protein of human BLK |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15874(BLK Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Raji cells, Primary antibody: PACO15874(BLK Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO15874(BLK Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. |
シノニム: | B lymphoid tyrosine kinase |
UniProt Protein Function: | BLK: a nonreceptor tyrosine kinase of the Src family. Expressed predominantly in B lymphocytes |
UniProt Protein Details: | Protein type:Protein kinase, TK; Kinase, protein; EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); TK group; Src family Chromosomal Location of Human Ortholog: 8p23-p22 Cellular Component: extrinsic to internal side of plasma membrane Molecular Function:protein binding; protein-tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding Biological Process: B cell receptor signaling pathway; innate immune response; positive regulation of insulin secretion; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation; T cell differentiation Disease: Maturity-onset Diabetes Of The Young, Type 11 |
NCBI Summary: | This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010] |
UniProt Code: | P51451 |
NCBI GenInfo Identifier: | 158936749 |
NCBI Gene ID: | 640 |
NCBI Accession: | P51451.3 |
UniProt Secondary Accession: | P51451,Q16291, Q96IN1, |
UniProt Related Accession: | P51451 |
Molecular Weight: | 505 |
NCBI Full Name: | Tyrosine-protein kinase Blk |
NCBI Synonym Full Names: | BLK proto-oncogene, Src family tyrosine kinase |
NCBI Official Symbol: | BLK |
NCBI Official Synonym Symbols: | MODY11 |
NCBI Protein Information: | tyrosine-protein kinase Blk; p55-Blk; b lymphocyte kinase; B lymphoid tyrosine kinase; BLK nonreceptor tyrosine kinase |
UniProt Protein Name: | Tyrosine-protein kinase Blk |
UniProt Synonym Protein Names: | B lymphocyte kinase; p55-Blk |
Protein Family: | Tyrosine-protein kinase |
UniProt Gene Name: | BLK |
UniProt Entry Name: | BLK_HUMAN |
Antibodies |
Anti-BLK Antibody (CAB7427) |
BLK Antibody (PACO00468) |
Phospho-BLK (Y501) Antibody (PACO05009) |
BLK Antibody (PACO08020) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
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